Chromatography column specifications

 

We manufacture glass chromatography columns in every possible size and configuration to your specifications. Chromatography columns are as various as chemists. Your choice will depend on the compounds you want to separate, the quantities, and your personal predilections...

We describe custom chromatography columns from the top down: see the sketch.

  • Joint style and size: for example, 24/40 Female, 24/40 Rodaviss (threaded top), 35/25 Socket joint.
  • Solvent reservoir size, if any.
  • Column tubing size and working length (the length of straight tubing, above the frit, if used). We normally use medium wall tubing for strength. A listing of tubing sizes is available here.
  • Porosity of fritted support, if any (typically coarse, medium, or P3 - between medium and coarse; see below).
  • Stopcock size (we generally use 2 mm bore for column diameters of 2" and below, 4 mm for larger, larger for humongous, per discussion).
  • Delivery tip style (angle cut drip tip, pipette-style drawn tip, Luer joint).
  • Plastic coating is an option

We like to provide fritted filters in your columns that work best for you. Many manufacturers use coarse or medium frits, corresponding to pore sizes of 40 - 60 µm and 10 - 16 µm. We have found that the European size designated P3 to be best for most column usage; its pore size is between coarse and medium: 16 - 40 µm. Since column packings are frequently called out with a particle size of 40µm, this porosity of frit holds up the packing well, but allows for good flow. We are happy to make whatever you choose.

You can see the range of standard frit diameters here.

We also manufacture flow control adapters, separable solvent reservoirs, and solvent addition funnels.

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